The group of Immunology and Genomics of the Marine Research Institute, CSIC, was appointed National Reference Laboratory for Bivalve Mollusc Diseases in 1995 (Council Directive 95/70/CE of 22 December 1995 introducing minimum Community measures necessary for the control of certain bivalve molluscs diseases).

The National Reference Laboratory for Bivalve Mollusc Diseases (Council Directive 2006/88/CE of 24 October 2006) determines, at the national level, the hazard index for certain diseases affecting bivalve molluscs. It has personnel with large experience in diagnostic techniques of both histology and molecular biology and is accredited by ENAC-ILAC according to the UNE-EN ISO 17025 standard for the following mollusc pathogens:


  • Marteilia spp. detection by histology and cytology in bivalve molluscs
  • Bonamia spp. detection by histology and cytology in flat oyster, Ostrea edulis
  • Perkinsus spp. detection by histology in clams


The rates can be checked in the following link. To download the assay request form, click here.


Among the tasks of the LNREMB we can mention the following:

  • Inform when the appearance of any one of the mollusc diseases (exotic and non-exotic) listed in the Directive is suspected.
  • Contribute to the identification of the sources of diseases through epizootic studies.
  • Coordinate with the European Reference Laboratory, the diagnostic methods used in the Member States. Training of experts in diagnosis according to these methods.
  • Periodically organize national comparative trials of the diagnostic procedures.





Antonio Figueras Huerta


Tel.: 986 231930 ext. 860280


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