Staff Publications Projects and contracts Thesis

In press

  • FERREIRA VR, AZENHA MA; MÊNA MT, MOURA C, PEREIRA CM, PÉREZ-MARTÍN RI, VÁZQUEZ JA, SILVA AF. Cationic imprinting of Pb (II) within composite networks based on bovine or fish chondroitin sulfate. Journal of Molecular Recognition (Aceptada en prensa). DOI 10.1002/jmr.2614.



  • FRANCO D, RODRÍGUEZ-AMADO I, AGREGÁN R, MUNEKATA P.E.S, VÁZQUEZ J.A, BARBA F.J, LORENZO J.M. 2018. Optimization of antioxidants extraction from peanut skin to prevent oxidative processes during soybean oil storage . Food Science and Technology , 88:1-8. DOI: 10.1016/j.lwt.2017.09.027.



  • BLANCO M., VÁZQUEZ J.A., PÉREZ-MARTÍN R.I., SOTELO  C.G. 2017. Hydrolysates of fish skin collagen: An opportunity for valorizing fish industry byproducts. Marine Drugs 15(5):131 DOI: 10.3390/md15050131
  • SAMAN, P., TUOHY, K.M., VÁZQUEZ, J.A., GIBSON, G., PANDIELLA, S.S. 2017. In vitro evaluation of prebiotic properties derived from rice bran obtained by debranning technology International Journal of Food Sciences and Nutrition 68(4):421-428 DOI: 10.1080/09637486.2016.1258045
  • AMADO, I.R., VÁZQUEZ, J.A., PASTRANA, L., TEIXEIRA, J.A. 2017 Microbial production of hyaluronic acid from agro-industrial by-products: Molasses and corn steep liquor Biochemical Engineering Journal 117:181-187 DOI: 10.1016/j.bej.2016.09.017
  • MENDES, M.C.D.Q., NUNES, J.M.C., MENEZES, M., FRAGA, S., RODRÍGUEZ, F., VÁZQUEZ, J.A., BLANCO, J., FRANCO, J.M., RIOBÓ, P. 2017 Toxin production, growth kinetics and molecular characterization of Ostreopsis cf. ovata isolated from Todos os Santos Bay, tropical southwestern Atlantic Toxicon 138:18-30 DOI: 10.1016/j.toxicon.2017.08.007
  • NOVOA-CARBALLAL, R., PÉREZ-MARTÍN, R., BLANCO, M., SOTELO, C.G., FASSINI, D., NUNES, C., COIMBRA, M.A., SILVA, T.H., REIS, R.L., VÁZQUEZ, J.A. 2017. By-products of Scyliorhinus canicula, Prionace glauca and Raja clavata: A valuable source of predominantly 6S sulphated chondroitin sulphate. Carbohydrate Polymers 157(10 February):31-37.
  • VÁZQUEZ, J.A., RAMOS, P., MIRÓN, J., VALVÁRCEL, J., SOTELO, C.G., PÉREZ-MARTÍN, R.I. 2017. Production of chitin from Penaeus vannamei by-products to pilot plant scale using a combination of enzymatic and chemical processes and subsequent optimization of the chemical production of chitosan by response surface methodology. Marine Drugs 15:180 (2017).
  • VÁZQUEZ, J.A., NORIEGA, D., RAMOS, P., VALCÁRCEL, J., NOVOA-CARBALLAL, R., PASTRANA, L., REIS, R.L., PÉREZ-MARTÍN, R.I. 2017. Optimization of high purity chitin and chitosan production from Illex argentinus pens by a combination of enzymatic and chemical processes. Carbohydrate Polymers 174:262-272.
  • RODRÍGUEZ, I., VÁZQUEZ, J.A., PASTRANA, L., KHUTORYANSKIY, V.V. 2017. Enhancement and inhibition effects on the corneal permeability of timolol maleate: Polymers, cyclodextrins and chelating agents. International Journal of Pharmaceutics 529(30 August):168-177.
  • VALCÁRCEL, J., NOVOA-CARBALLAL, R., PÉREZ-MARTÍN, R.I., REIS, R.L., VÁZQUEZ, J.A. 2017. Glycosaminoglycans from marine sources as therapeutic agents. Biotechnology Advances 35(6):711-725.
  • SOUSA, S.C., VÁZQUEZ, J.A., PÉREZ-MARTÍN, R.I., CARVALHO, A.P., GOMES, A.M. 2017. Valorization of by-products from commercial fish species: Extraction and chemical properties of skin gelatins. Molecules 22:1545.
  • VÁZQUEZ, J.A., BLANCO, M., MASSA, A.E., RODRÍGUEZ-AMADO, I., PÉREZ-MARTÍN, R.I. Production of fish protein hydrolysates from Scyliorhinus canicula discards with antihypertensive and antioxidant activities by enzymatic hydrolysis and mathematical optimization using response surface methodology. Marine Drugs 15 (10):306  doi:10.3390/md15100306



  • FRANCO D, PATEIRO M, ROIS D, VÁZQUEZ JA, LORENZO, JM. 2016. Effects of Caponization on Growth Performance, Carcass and Meat Quality of Mos Breed Capons Reared in Free-Range Production System. Annals of Animal Science 16(3):909–929 DOI: 10.1515/aoas-2016-000
  • FRANCO D, PATEIRO M, AMADO IR, PEDROUSO ML, ZAPATA C, VAZQUEZ JA, LORENZO JM. 2016. Antioxidant ability of potato (Solanum tuberosum) peel extracts to inhibit soybean oil oxidation. European Journal of Lipid Science and Technology, 118 (12):1891-1902. DOI: 10.1002/ejlt.201500419
  • VÁZQUEZ JA, CAPRIONI R, NOGUEIRA M, MENDUIÑA A, RAMOS P, PÉREZ-MARTÍN R.I.2016. Valorisation of effluents obtained from chemical and enzymatic chitin production of Illex argentinus pen by-products as nutrient supplements for various bacterial fermentations Biochemical. Engineering Journal ,116 pp. 34 -44 .
  • AMADO IR, VÁZQUEZ JA, PASTRANA L, TEIXEIRA JA. 2017. Microbial production of hyaluronic acid from agro-industrial by-products: Molasses and corn steep liquor.  Biochemical Engineering Journal, 117: 181-187. DOI:10.1016/j.bej.. 2016..09.017.
  • NOVOA-CARBALLAL R, PÉREZ-MARTÍN R, BLANCO M, SOTELO CG, FASSINI D, NUNES C, COIMBRA MA, SILVA TH, REIS RL, VÁZQUEZ JA. 2017. By-products of Scyliorhinus canicula, Prionace glauca and Raja clavata: A valuable source of predominantly 6S sulfated chondroitin sulfate. Carbohydrate Polymers,  157: 31-37. DOI:10.1016/j.carbpol.. 2016..09.050
  • AMADO IR, GONZÁLEZ MP, MURADO MA, VÁZQUEZ JA. 2016. Shrimp wastewater as a source of astaxanthin and bioactive peptides. Journal of Chemical Technology and Biotechnology , 91(3): 793-805. DOI:10.1002/jctb.4647.
  • FERNÁNDEZ-PARDO A, COSTA F DA, RIAL D, NOVOA S, MARTÍNEZ-PATINO D, VÁZQUEZ J A. 2016. Use of response surface methodology to determine optimum diets for Venerupis corrugata larvae: effects of ration and microalgal assemblages. Aquaculture, 452: 283-290 .
  • AMADO I R, VÁZQUEZ J A, PASTRANA L, TEIXEIRA J A. 2016. Cheese whey: A cost-effective alternative for hyaluronic acid production by Streptococcus zooepidemicus.Food Chemistry, 198: 54-61.
  • PINELA J, PRIETO M A, BARREIRO M F, CARVALHO A M, OLIVEIRA M B, VÁZQUEZ J A . 2016. Optimization of microwave-assisted extraction of hydrophilic and lipophilic antioxidants from a surplus tomato crop by response surface methodology .  Food and Bioproducts Processing,  98: 283-298.
  • VÁZQUEZ J A, BLANCO M, FRAGUAS J, PASTRANA L, PÉREZ-MARTÍN R I. 2016. Optimisation of the extraction and purification of chondroitin sulphate from head by-products of Prionace glauca by environmental friendly processes. Food Chemistry, 198: 28-35.



  • PRIETO MA, VÁZQUEZ JA, MURADO MA. 2015. Crocin bleaching antioxidant assay revisited. Application to microplate to analyse antioxidant and prooxidant activities. Food Chemistry, 167: 299-310.
  • RODRÍGUEZ-AMADO I, VÁZQUEZ JA, MURADO MA, GONZÁLEZ MP. 2015. Recovery of astaxanthin from shrimp cooking wastewater. Optimization of astaxanthin extraction by response surface methodology and kinetic studies. Food and Bioprocess Technology, 8: 371-381.
  • PRIETO MA, CURRANT T, GOWEN A, VÁZQUEZJA. 2015. An efficient methodology for quantification of synergy and antagonism in single electron transfer antioxidant assays. Food Research International, 67: 284-298.
  • PRIETO MA, VÁZQUEZ JA, MURADO MA. 2015. A new and general model to describe, characterize, quantify and classify the interactions of temperature and pH on the activity of enzymes. Analyst, 140: 3587-3602.
  • PRIETO MA, PRIETO I, VÁZQUEZ JA, FERREIRA ICFR. 2015. An environmental management industrial solution for the treatment and reuse of mussel wastewaters. Science of the Total Environment, 538: 117-128.
  • BLANCO M, FRAGUAS J, SOTELO CG, PÉREZ-MARTÍN RI, VÁZQUEZ JA. 2015. Production of chondroitin sulphate from head, skeleton and fins of Scyliorhinus canicula by-products by combination of enzymatic, chemical precipitation and ultrafiltration methodologies. Marine Drugs, 13: 3287-3308.
  • VÁZQUEZ JA, PASTRANA L, PIÑEIRO C, TEIXEIRA JA, PÉREZ-MARTÍN RI, AMADO IR. 2015. Production of hyaluronic acid by Streptococcus zooepidemicus on protein substrates obtained from Scyliorhinus canicula discards. Marine Drugs, 13: 6537-6549.
  • RODRÍGUEZ-AMADO IR, VÁZQUEZ JA. 2015. Mussel processing wastewater: a low-cost substrate for the production of astaxanthin by Xanthophyllomyces dendrorhous. Microbial Cell Factories, 14: 177.
  • SALGADO P, VÁZQUEZ JA, RIOBÓ P, FRANCO JM, FIGUEROA RI, KREMP A, BRAVO I. 2015. A kinetic and factorial approach to study the effect of temperature and salinity on growth and toxin production by the dinoflagellate Alexandrium ostenfeldii from the Baltic Sea. PLoS ONE, 10: e0143021.
  • PRIETO MA, MURADO MA, BARTLETT J, MAGETTE WL, CURRAN TP. 2015. Mathematical model as a standard procedure to analyze small and large water distribution networks. Journal of Cleaner Production, 106: 541-554.
  • PATEIRO M, LORENZO JM, VÁZQUEZ JA, FRANCO D. 2015. Oxidation stability of pig liver pâté with increasing levels of natural antioxidants (grape and tea). Antioxidants, 4: 102-123.
  • SOUSA F, Lorenzo JM, VÁZQUEZ JA, CANTALAPIEDRA J, FRANCO D. 2015. Mirandesa breed calves: Growth performance and carcass characterization affected by sex and livestock production system. Journal of Animal Nutrition, 1: 2.
  • PLANAS M, VÁZQUEZ JA, NOVOA B. 2015. Stimulative effect of lactic acid bacteria in the growth of the microalgae Isochrysis galbana. Journal of Coastal Life Medicine, 3: 925-930.
  • SOTELO CG, SIEIRO P, MAROTO J, VÁZQUEZ JÁ, PÉREZ-MARTÍN RI, SILVA TH, REIS RL (coordinadores). 2015. Valorización de Recursos Marinos: Biomateriales en regeneración de tejidos y liberación de fármacos. Grupo de Bioquímica de Alimentos (IIM-CSIC). ISBN: 978-84-608-3120-4.



  • AMADO IR, FRANCO D, SÁNCHEZ M, ZAPATA C,  VÁZQUEZ JA. 2014. Optimisation of antioxidant ex – traction from Solanum tuberosum potato peel waste  by surface response methodology.  Food Chemistry, 165: 290-299. DOI: 10.1016/j.foodchem.2014.05.103.
  • AMADO IR, VÁZQUEZ JA, GONZALEZ P, ESTE- BAN-FERNANDEZ D, CARRERA M, PIÑEIRO C. 2014.  Identification of the major ACE-Inhibitory peptides  produced by enzymatic hydrolysis of a protein con- centrate from cuttlefish wastewater.  Marine Drugs, 12(3): 1390-1405. DOI: 10.3390/md12031390.
  • AMADO IR, VÁZQUEZ JA, GUERRA NP, PASTRANA  L. 2014. Thermal resistance of Salmonella enterica,  Escherichia coli and Staphylococcus aureus isola- ted from vegetable feed ingredients.  Journal of the  Science of Food and Agriculture, 94(11): 2274-2281.  DOI: 10.1002/jsfa.6554.
  • FRANCO D, VAZQUEZ JA, LORENZO JM. 2014.  Growth performance, carcass and meat quality  of the Celta pig crossbred with Duroc and Lan- drance genotypes.  Meat Science, 96: 195-202. DOI:  10.1016/j.meatsci.2013.06.024.
  • FUCIÑOS C, FUCIÑOS P, MÍGUEZ M, KATIME I,  PASTRANA LM, RUA ML. 2014. Temperature- and  pH-sensitive nanohydrogels of poly(N-isopropyla- crylamide) for food packaging applications: Mo – delling the swelling-collapse behaviour.  PLoS ONE, 9(2): e87190. DOI: 10.1371/journal.pone.0087190.
  • FUCIÑOS P, ATANES E, LÓPEZ-LÓPEZ O, SOLAROLI  M, CERDÁN ME, GONZÁLEZ-SISO MI, PASTRANA  L, RÚA ML. 2014. Cloning, expression, purification  and characterization of an oligomeric His-tagged  thermophilic esterase from Thermus thermophi- lus HB27.  Process Biochemistry, 49(6): 927-935. DOI:  10.1016/j.procbio.2014.03.006.
  • LAGE IP, GUTIÉRREZ-SANTIAGO A, LAGE MÁP. 2014.  Determination of feedback in judo by means of  T-patterns.  Motriz. Revista de Educacao Fisica, 20(1):  47-53. DOI: 10.1590/S1980-65742014000100007.
  • LORENZO JM, SINEIRO J, AMADO IR, FRANCO D. 2014. Influence of natural extracts on the shelf life  of modified atmosphere-packaged pork patties.  Meat Science, 96: 526-534. DOI: 10.1016/j.meats- ci.2013.08.007.
  • MURADO MA, PRIETO MA. 2014. Oversimplifica- tion and overstandardization in biological me – thods: Sperm bioassays in ecotoxicology as a case  of study and a proposal for their reformulation.  The Scientific World Journal, 2014: id936202. DOI:  10.1155/2014/936202.
  • PATEIRO M, LORENZO JM, AMADO IR, FRANCO  D. 2014. Effect of addition of green tea, chestnut  and grape extract on the shelf-life of pig liver pâté.  Food Chemistry, 147: 386-394. DOI: 10.1016/ chem.2013.09.153.
  • PRIETO LAGE I, GUTTIÉRREZ-SANTIAGO A, PRIE- TO LAGE MÁ. 2014. The teaching-learning process  of judo techniques improved using knowledge of errors. Tai-otoshi as a case study.  International Jour – nal of Performance Analysis in Sport, 14(3): 841-851.
  • PRIETO MA, MURADO MA, VÁZQUEZ JA. 2014.  Quantification, characterization and description of  synergy and antagonism in the antioxidant respon- se.  Food Research International, 60: 218-229. DOI:  10.1016/j.foodres.2013.09.033.
  • PRIETO MA, MURADO MA, VÁZQUEZ JA, CURRAN  T P. 2014. Analytical criteria to quantify and compare  the antioxidant and pro-oxidant capacity in com- petition assays: The bell protection function.  Food  Research International, 60: 48-58. DOI: 10.1016/ – dres.2013.12.037.
  • PRIETO MA, VÁZQUEZ JA. 2014. A time-dose mo – del to quantify the antioxidant responses of the  oxidative hemolysis inhibition assay (OxHLIA) and  its extension to evaluate other hemolytic effectors.  BioMed Research International, 2014: id632971. DOI:  10.1155/2014/632971.
  • PRIETO MA, VÁZQUEZ JA. 2014. In vitro determi- nation of the lipophilic and hydrophilic antioxidant  capacity of unroasted coffee bean extracts and their  synergistic and antagonistic effects.  Food Research  International, 62: 1183-1196. DOI: 10.1016/ – dres.2014.05.030.
  • PRIETO MA, VÁZQUEZ JA, MURADO MA. 2014. A  critical point: The problems associated with the va- riety of criteria to quantify the antioxidant capacity.  Journal of Aagricultural and Food Chemistry, 62(24):  5472-5484. DOI: 10.1021/jf5005995.
  • PRIETO MA, VÁZQUEZ JA, MURADO MA. 2014. A  new mathematical model to quantify and characte – rize the response to pro- and anti-oxidants of the co – pper-induced oxidation of LDL assay. A tool for exa- mination of potential preventive compounds and  clinical risk prediction.  Food Research International, 66: 501-513. DOI: 10.1016/j.foodres.2014.07.046.
  • PRIETO MA, VÁZQUEZ JA, MURADO MA. 2014.  Mathematical modeling of area under the curve  assessment criteria to quantify the antioxidant  and pro-oxidant capacity: Coffee extracts as a case  study.  Food Research International, 64: 962-975. DOI:  10.1016/j.foodres.2014.05.048.
  • RIAL D, MURADO MA, BEIRAS R, VÁZQUEZ JA. 2014.  Toxicity of four spill-treating agents on bacterial  growth and sea urchin embryogenesis.  Chemosphere, 104: 57-62. DOI: 10.1016/j.chemosphere.2013.10.057.
  • RIAL D, VÁZQUEZ JA, MURADO MA. 2014. Toxicity  of spill-treating agents and oil to sea urchin embr – yos.  Science of the Total Environment, 472: 302-308.  DOI: 10.1016/j.scitotenv.2013.11.030.
  • VÁZQUEZ JA. 2014. Modeling of chemical inhibi- tion from amyloid protein aggregation kinetics.  BMC Pharmacology & Toxicology, 15(1): 9. DOI:  10.1186/2050-6511-15-9.
  • VÁZQUEZ JA, RIAL D. 2014. Inhibition of selected  bacterial growth by three hydrocarbons: Mathema- tical evaluation of toxicity using a toxicodynamic  equation.  Chemosphere, 112: 56-61. DOI: 10.1016/j. chemosphere.2014.03.008.



  • TORRADO A, VAZQUEZ JA, PRIETO MA, FUCINOS P, MONTEMAYOR MI, PASTRANA L, GONZALEZ MP, MURADO, MA. 2013. Amylase production by Aspergillus oryzae in a solid-state bioreactor with fed-batch operation using mussel processing wastewaters as feeding medium. Journal of Chemical Technology and Biotechnology, 88: 226-236.
  • FRANCO D, ROIS D, VAZQUEZ JA, LORENZO JM. 2013. Carcass morphology and meat quality from roosters slaughtered at eight months affected by genotype and finishing feeding. Spanish Journal of Agricultural Research, 11: 382-393.
  • VAZQUEZ JA, AMADO IR, MONTEMAYOR MI, FRAGUAS J, GONZALEZ M.P, MURADO MA. 2013. Chondroitin sulphate, hyaluronic acid and chitin/ chitosan production using marine waste sources: characteristics, applications and eco-friendly processes: A review. Marine Drugs, 11: 747-774.
  • FRANCO D, CRECENTE S, VAZQUEZ JA, GAMEZ M, LORENZO JM. 2013. Effect of cross breeding and amount of finishing diet on growth parameters, carcass and meat composition of foals slaughtered at 15 months of age. Meat Science, 93: 547-556. RIAL D, RADOVIC JR, BAYONA JM, MACRAE K, THOMAS KV, BEIRAS R. 2013. Effects of simulated weathering on the toxicity of selected crude oils and their components to sea urchinembryos. Journal of Hazardous Materials, 260: 67-73.
  • RIAL D, MURADO MA, MENDUINA A, FUCINOS P, GONZALEZ M.P, MIRON J, VAZQUEZ JA. 2013. Effects of spill-treating agents on growth kinetics of marine microalgae. Journal of Hazardous Materials, 263: 374-381.
  • WARDHANI DH, FUCINOS P, VAZQUEZ JA, PANDIELLA SS. 2013. Inhibition kinetics of lipid oxidation of food models by using antioxidant extract of fermented soybeans. Food Chemistry, 113: 837-844.
  • SANCHEZ A, VAZQUEZ JA, QUINTEIRO J, SOTELO CG. 2013. Modelling real-time PCR kinetics: Richards reparameterised equation for quantitative estimation of European hake (Merluccius merluccius). Journal of Agricultural and Food Chemistry, 61: 3488-3493.
  • MURADO MA, PRIETO MA. 2013. NOEC and LOEC as merely concessive expedients: Two unambiguous alternatives and some criteria to maximize the efficiency of dose-response experimental designs. Science of the Total Environment, 461-462: 576-586.
  • MURADO MA, PRIETO MA. 2013. Dose-Response analysis in the joint action of two effectors. A new approach to simulation, identification and modelling of some basic interactions. PlosOne, 8: e61391.
  • AMADO IR, VAZQUEZ JA, FUCINOS P, MENDEZ J, PASTRANA L. 2013. Optimization of antimicrobial combined effect of organic acids and temperature on foodborne Salmonella and Escherichia coli in cattle feed by response surface methodology. Foodborne Pathogens and Disease, 10: 1030-1036.
  • AMADO IR, VAZQUEZ JA, GONZALEZ M.P, MURADO MA. 2013. Production of antihypertensive and antioxidant activities by enzymatic hydrolysis of protein concentrates recovered by ultrafiltration from cuttlefish processing wastewaters. Biochemical Engineering Journal, 76: 43-54.
  • RIAL D, VAZQUEZ JA, MENDUINA A, GARCIA AM, GONZALEZ MP, MIRON J, MURADO MA. 2013. Toxicity of binary mixtures of oil fractions to sea urchin embryos. Journal of Hazardous Materials, 263: 431-440.
  • PRIETO MA, MURADO MA, VAZQUEZ JA, ANDERS Y, CURRAN TP. 2013. A new microplate procedure for simultaneous assessment of antiand pro-oxidants, using crocin and β-carotene bleaching methods in a single combined assay. Tea extracts as a case study. Food Research International, 53: 836-846.
  • LORENZO JM, GONZALEZ-RODRIGUEZ RM, SANCHEZ M, AMADO IR, FRANCO D. 2013. Effects of natural (grape seed and chestnut extract) and synthetic antioxidants (buthylatedhydroxytoluene, BHT) on the physical, chemical, microbiological and sensory characteristics of dry cured sausage “chorizo”. Food Research International, 54, 611-620.
  • ESTEVEZ N, FUCINOS P, SOBROSA AC, PASTRANA L, PEREZ N, RUA ML. 2012. Modelling the angiotensin- converting enzyme inhibitory activity of peptide mixtures obtained from cheese whey hydrolysates using concentration-response curves. Biotechnology Progress, 28(5): 1197-1206.
  • FRANCO D, ROIS D, VAZQUEZ JA, LORENZO JM. 2012. Comparison of growth performance, carcass components and meat quality, between Mos rooster (Galician Indigenous Breed) and Sasso T-44 line slaughtered at 10 months. Poultry Science, 91(5): 1227-1239.

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