Innovation Capabilities & Products

Method described in: Exler, O., L.T. Antelo, J.A. Egea, A.A. Alonso and J.R. Banga (2008) A Tabu search-based algorithm for mixed-integer nonlinear problems and its application to integrated process and control system design. Computers & Chemical Engineering, 32(8):1877-1891.

Software available upon request (email us if interested).

Multi-scale modeling for flexible decision-making and optimization of complex processes (i.e., sterilization) based on safety and quality control of food products using non-invasive techniques (software sensors, etc).

Studies on the structure of the genome of marine organisms, including gene mapping, DNA sequencing and how the complete set of RNA transcripts is produced by the genome and affected by development, diseases, or environmental factors conditioning the phenotype and particularly proteomics and metabolomics, always applying the most advanced techniques (ATAC-seq, MethylCap-Seq, RNA-seq, recombinant DNA technology, knockin and knockout CRISPR/Cas9, enhancer detector (ZED),Tol2 kit and BAC transgenic technologies, etc.).

PREMER (Parallel Reverse Engineering with Mutual information & Entropy Reduction) is an open-source, multi-platform software tool for inferring network structures from data using information-theoretic measures. While this general purpose tool has been developed with biological networks in mind, it can be applied to other areas.

More information here.

Optimization of multitrophic culture systems in open and closed aquaculture infrastructures, ranging from recirculation fish-macroalgae aquaculture systems, with special focus on the effect of the resultant microbiomes on animal welfare, to the adjustment of low-trophic multi-species aquaculture systems in the ocean.

The method is described in Schlater, M., J. A. Egea, J. R. Banga (2009) Extended ant colony optimization for non-convex mixed integer nonlinear programming. Computers & Operations Research 36(7): 2217-2229.

Software available upon request (email us if interested).

Device to monitor the physiological status of up to 64 bivalves in their culture system in real time. 

The monitoring system is based on the analysis of micro-movements of bivalves related to valve opening (valvometry). This technique has been confirmed by recent studies as a very promising technique to detect harmful algal blooms or ocean acidification episodes.

The prototype is being adapted to increase its portability and autonomy. For further information, please contact us by e-mail.

Development of chemical (combinations of disinfectants, essential oils) and biological (enzymes, phages) strategies that are effective for removing monospecific and mixed microbial biofilms from surfaces in the food industry. Biocide testing and development of better biocide dosage strategies for the food industry, ensuring food safety while avoiding antimicrobial resistance acquisition.

Pathogen detection and identification in wild and farmed animals, as well as in seafood products. Evaluation of the relationship between pathogen incidence and various environmental and physiological aspects to provide risk assessments for target pathogens.

BioPreDyn-Bench is a suite of benchmark problems for dynamic modeling in systems biology. Currently, it contains six challenging parameter estimation problems, which aspire to serve as reference test cases in this area. This set includes medium- and large-scale kinetic models of E.coli, S. cerevisiae, D. melanogaster, Chinese Hamster Ovary (CHO) cells and a generic signaling network. The level of description includes metabolism, transcription, signal transduction and development.

More information here.